International Journal of High Throughput Screening
Open access peer-reviewed scientific and medical journals.
Dove Medical Press is now a member of the Open Access Initiative
An Author's Guide
A guide to help authors get their paper published.
Support Open Access and Dove Press
Promotional Article Monitoring - further details
Favored Author Program
Real benefits for authors, including fast-track processing of papers.
An overview of urinary proteomics applications in human diseases
(5171) Total Article Views
Authors: Gayathri Gopalan, Veena S Rao, Vijay V Kakkar
Published Date November 2010
Volume 2010:1 Pages 183 - 192
Gayathri Gopalan1, Veena S Rao1, Vijay V Kakkar2
1Tata Proteomics and Coagulation Unit, Thrombosis Research Institute, Bangalore, India; 2Thrombosis Research Institute, London, United Kingdom
Abstract: A major challenge in clinical proteomics is the identification of reliable biomarkers that help early diagnosis of disease, which will not only assist the clinician but also contribute to the development of personalized medicine. Urinary proteomic studies provide information on urine composition along with insight into renal physiology, kidney disease states, and other associated diseases. In the past decade, technical advances in the design of highly sensitive mass spectrometers and accurate protein quantitation technologies have led to the application of urinary proteomics in diverse research areas, including basic biomedical and clinical sciences. Of specific interest is the identification of biomarkers by virtue of improvements in instrumentation, bioinformatics, and database development. Here, we review recent discoveries in urinary proteomics with respect to identifying novel biomarker, its current challenges, and potential for future research.
Keywords: urinary proteomics, biomarker, mass spectrometry
Cannotea Citeulike Del.icio.us Facebook LinkedIn Twitter
Other articles by Dr Veena Rao
Readers of this article also read:
"You do a tremendous job!!" Ruben Restrepo, University of Texas Health Science Center, San Antonio.
- MLA'14 -
May 16–21, 2014
- Does wine prevent dementia?
- Wine consumers’ environmental knowledge and attitudes: Influence on willingness to purchase
- China’s role in global competition in the wine industry: A new contestant and future trends
- Influence of sodium chloride on wine yeast fermentation performance