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Worsened hypertension control induced by aripiprazole

Authors Yasui-Furukori N, Fujii A

Received 12 February 2013

Accepted for publication 19 March 2013

Published 15 April 2013 Volume 2013:9 Pages 505—507

DOI https://doi.org/10.2147/NDT.S43950

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Norio Yasui-Furukori, Akira Fujii

Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan

Abstract: Aripiprazole is widely used in the treatment of schizophrenia and bipolar disorders. Although antipsychotics generally have hypotensive effects, two cases were identified that demonstrated hypertension during the switch from other antipsychotics to aripiprazole. The hypertensive state of these patients recovered after switching back to other antipsychotics, and these cases suggest that aripiprazole may lead to hypertension.

Keywords: hypertension, aripiprazole, dopamine antagonist, 5-HT1a

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