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Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

Authors Seidensticker F, Neubauer A, Wasfy, Stumpf, Thurau, Kampik A, Kernt M

Published 29 November 2011 Volume 2011:5 Pages 1667—1671

DOI https://doi.org/10.2147/OPTH.S26224

Review by Single-blind

Peer reviewer comments 3


Florian Seidensticker1, Aljoscha S Neubauer1, Tamer Wasfy1,2, Carmen Stumpf1, Stephan R Thurau1,*, Anselm Kampik1, Marcus Kernt1,*
1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany; 2Department of Ophthalmology, Tanta University, Tanta, Egypt
*Both authors contributed equally to this work

Background and objectives: Detection of peripheral fundus autofluorescence (FAF) using conventional scanning laser ophthalmoscopes (SLOs) is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.
Study design/materials and methods: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.
Results: Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.
Conclusion: Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.

Keywords: fundus autofluorescence (FAF), Optomap, wide-field scanning laser ophthalmoscopy, imaging, uveitis, visual field

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