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Visual acuity, endothelial cell density and polymegathism after iris-fixated lens implantation

Authors Nassiri N, Ghorbanhosseini S, Jafarzadehpur E, Kavousnezhad S, Nassiri N, Sheibani K

Received 19 November 2017

Accepted for publication 15 February 2018

Published 29 March 2018 Volume 2018:12 Pages 601—605


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser

Nader Nassiri,1 Saeedeh Ghorbanhosseini,2 Ebrahim Jafarzadehpur,2 Sara Kavousnezhad,3 Nariman Nassiri,4 Kourosh Sheibani5

1Imam Hossein Medical Center, Shahid Beheshti University of Medical Science, Tehran, Iran; 2Department of Optometry, Iran University of Medical Sciences, Tehran, Iran; 3Vanak Eye Clinic, Tehran, Iran; 4Jules Stein Eye Institute, University of California at Los Angeles, Los Angeles, CA, USA; 5Basir Eye Health Research Center, Basir Eye Clinic, Tehran, Iran

Purpose: The purpose of this study was to evaluate the visual acuity as well as endothelial cell density (ECD) and polymegathism after iris-fixated lens (Artiflex® AC 401) implantation for correction of moderate to high myopia.
Patients and methods: In this retrospective cross-sectional study, 55 eyes from 29 patients undergoing iris-fixated lens implantation for correction of myopia (−5.00 to −15.00 D) from 2007 to 2014 were evaluated. Uncorrected visual acuity, best spectacle-corrected visual acuity, refraction, ECD and polymegathism (coefficient of variation [CV] in the sizes of endothelial cells) were measured preoperatively and 6 months postoperatively.
Results: In the sixth month of follow-up, the uncorrected vision acuity was 20/25 or better in 81.5% of the eyes. The best-corrected visual acuity was 20/30 or better in 96.3% of the eyes, and more than 92% of the eyes had a refraction score of ±1 D from the target refraction. The mean corneal ECD of patients before surgery was 2,803±339 cells/mm2, which changed to 2,744±369 cells/mm2 six months after surgery (p=0.142). CV in the sizes of endothelial cells before the surgery was 25.7%±7.1% and six months after surgery it was 25.9%±5.4% (p=0.857).
Conclusion: Artiflex iris-fixated lens implantation is a suitable and predictable method for correction of moderate to high myopia. There was no statistically significant change in ECD and polymegathism (CV in the sizes of endothelial cells) after 6 months of follow-up.

Keywords: cornea, endothelial cell, density, Artiflex, refractive surgery

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