Back to Journals » Journal of Multidisciplinary Healthcare » Volume 3

Uses and benefits of omega-3 ethyl esters in patients with cardiovascular disease

Authors Levantesi G, Silletta MG, Marchioli R

Published 7 July 2010 Volume 2010:3 Pages 79—96

DOI https://doi.org/10.2147/JMDH.S4743

Review by Single anonymous peer review

Peer reviewer comments 2



Giacomo Levantesi, Maria Giuseppina Silletta, Roberto Marchioli

Laboratory of Clinical Epidemiology of Cardiovascular Disease, Consorzio Mario Negri Sud, Chieti, Italy

Abstract: Much evidence on the favorable effects of omega-3 ethyl esters on cardiovascular morbidity and mortality has been obtained in studies performed in healthy subjects and in different clinical settings. Here the clinical effects of omega-3 ethyl ester administration in patients with previous myocardial infarction or heart failure are reviewed, together with a discussion of underlying mechanisms of action. The pharmacokinetic and pharmacodynamic properties of omega-3 ethyl esters, as well as evidence concerning their safety and tolerability, are also reported.

Keywords: omega-3 ethyl esters, myocardial infarction, heart failure

Creative Commons License © 2010 The Author(s). This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.