Back to Journals » Clinical Interventions in Aging » Volume 14

Usefulness of patellar cartilage cross-sectional area for knee tibiofemoral osteoarthritis in elderly

Authors Bang YS, Park J, Kim J, Choi YS, Lim YS, Cho HR, Kim YU

Received 12 February 2019

Accepted for publication 22 May 2019

Published 5 June 2019 Volume 2019:14 Pages 1021—1026


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Richard Walker

Yun-Sic Bang,1 Junbeom Park,1 Jihee Kim,1 Young-Soon Choi,2 Young Su Lim,2 Hyung Rae Cho,3 Young Uk Kim2

1Department of Anesthesiology and Pain Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea; 2Department of Anesthesiology and Pain Medicine, Catholic Kwandong University, College of Medicine, International ST. Mary’s Hospital, Incheon, Republic of Korea; 3Department of Anesthesiology and Pain Medine, Myongji Hospital, Hanyang University Medical Center, Seoul, Republic of Korea

Purpose: Knee tibiofemoral osteoarthritis (KOA) is a major health problem, affecting approximately 30% of elderly. Several studies have reported that the loss of patellar cartilage is associated with an increased risk of KOA. However, no study has reported the optimal cut off value of patellar cartilage cross-sectional area (PCA) in KOA. We hypothesize that PCA is a new sensitive morphologic parameter in the diagnosis of KOA. The purpose of this study was to determine whether PCA could be used as an important adjuvant morphological parameter in the diagnosis of KOA.
Patients and methods: Data regarding PCA were collected from 88 subjects with KOA. A total of 77 subjects in the control group underwent knee MRI as part of nonsymptomatic medical examination. T2-weighted axial images were acquired from both groups. Using a picture archiving communications system, we analyzed the cross-sectional area of the patellar cartilage on MRI.
Results: The average PCA was 98.66±22.18 mm2, in the control group, which was significantly (p<0.001) higher than that (59.43±16.11 mm2,) in the KOA group. Receiver operator haracteristic curve analysis was computed to determine the validity of PCA as a predictor of KOA. In the KOA group, the optimal cut offpoint was 76.06 mm,2 with sensitivity of 83.0%, specificity of 83.1%, and AUC of 0.94 (95% CI: 0.90–0.97).
Conclusions: Lower PCA values were associated with a higher possibility of KOA. The optimal cutoff score of PCA might be used to facilitate the evaluation of patients with KOA.

Keywords: knee tibiofemoral osteoarthritis, patellar cartilage, cross-sectional area, cartilage loss

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]