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Update on tolterodine extended-release for treatment of overactive bladder

Authors Omotosho T, Chen G

Published 23 November 2010 Volume 2010:2 Pages 185—191

DOI https://doi.org/10.2147/RRU.S7232

Review by Single-blind

Peer reviewer comments 3


Tola Omotosho, Chi Chiung Grace Chen
Women’s Center for Pelvic Health, Department of Gynecology and Obstetrics, Johns Hopkins School of Medicine, Baltimore, MD, USA

Abstract: Overactive bladder is a prevalent condition which negatively impacts quality of life and puts a significant economical burden on society. First-line therapy often includes pharmacotherapy with antimuscarinic medications, and numerous research studies have demonstrated that tolterodine extended-release (ER) is an efficacious and tolerable formulation of this class of medication. This review provides an update on the clinical use of tolterodine ER, detailing the current literature on its efficacy, tolerability, adverse effects, and comparability with other commonly prescribed medications for the treatment of overactive bladder.

Keywords: antimuscarinics, efficacy, quality of life, overactive bladder, tolterodine, urgency, urge urinary incontinence

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