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Update on thyroid eye disease and management

Authors Bothun E, Scheuer RA, Harrison A, Lee M

Published 15 October 2009 Volume 2009:3 Pages 543—551

DOI https://doi.org/10.2147/OPTH.S5228

Review by Single-blind

Peer reviewer comments 3


Erick D Bothun,1,2 Ryan A Scheurer,1 Andrew R Harrison,1,3 Michael S Lee1,4,5

1Departments of Ophthalmology, 2Pediatrics, 3Otolaryngology, 4Neurosurgery, and 5Neurology, University of Minnesota, Minneapolis, Minnesota, USA

Abstract: Thyroid eye disease is a heterogeneous autoimmune orbital reaction typically manifesting in middle age. The inflammation may parallel or remain isolated from a related inflammatory cascade in the thyroid called Graves’ disease. The orbital manifestations can lead to severe proptosis, dry eyes, strabismus, and optic neuropathy. In this article, we will discuss this unique condition including the ophthalmic findings and management.

Keywords: Graves’ disease, thyroid eye disease, proptosis, orbital decompression, enlarged extraocular muscles

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