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Update on obstructive sleep apnea and its relation to COPD

Authors Mieczkowski B, Ezzie ME

Received 26 November 2013

Accepted for publication 24 January 2014

Published 8 April 2014 Volume 2014:9(1) Pages 349—362

DOI https://doi.org/10.2147/COPD.S42394

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Brian Mieczkowski, Michael E Ezzie

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Ohio State University, Wexner Medical Center, Columbus, OH, USA

Abstract: Chronic obstructive pulmonary disease (COPD) is a common and preventable lung disease that affects millions of people in the United States. Sleep disorders including obstructive sleep apnea (OSA) are also common. It is not surprising that many people with COPD also suffer from OSA. This relationship, however, puts people at risk for more nocturnal desaturations and potential complications related to this, including pulmonary hypertension and heart rhythm disturbances. This update focuses on the physiology of sleep disturbances in COPD as well as the clinical implications of OSA in COPD.

Keywords: sleep, chronic obstructive pulmonary disease, nocturnal hypoxemia, obstructive sleep apnea

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