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Underuse of epinephrine for the treatment of anaphylaxis: missed opportunities

Authors Prince BT, Mikhail I, Stukus DR

Received 9 December 2017

Accepted for publication 9 January 2018

Published 20 June 2018 Volume 2018:11 Pages 143—151


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Luis Garcia-Marcos

Benjamin T Prince, Irene Mikhail, David R Stukus

Division of Allergy and Immunology, Nationwide Children’s Hospital, The Ohio State University College of Medicine, Columbus, OH, USA

Abstract: Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient- and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.

Keywords: anaphylaxis, epinephrine, emergency department, food allergy

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