Understanding Patient Perspectives and Awareness of the Impact and Treatment of Anemia with Chronic Kidney Disease: A Patient Survey in China
Received 10 November 2020
Accepted for publication 20 January 2021
Published 22 February 2021 Volume 2021:14 Pages 53—64
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Professor Pravin Singhal
Chuan-Ming Hao,1 Eric T Wittbrodt,2 Eirini Palaka,3 Nicolas Guzman,4 Alicia Dunn,5 Susan Grandy6
1Fudan University, Huashan Hospital, Shanghai, People’s Republic of China; 2Biopharmaceuticals Medical Unit, AstraZeneca, Gaithersburg, MD, USA; 3Biopharmaceuticals Global Market Access, AstraZeneca, Cambridge, UK; 4Global Medicines Development, AstraZeneca, Gaithersburg, MD, USA; 5AstraZeneca Global Corporate Affairs Gaithersburg, Gaithersburg, MD, USA; 6Biopharmaceuticals Global Market Access, AstraZeneca, Gaithersburg, MD, USA
Correspondence: Chuan-Ming Hao
Fudan University, Huashan Hospital, Shanghai, People’s Republic of China
Background: Anemia is a common complication of chronic kidney disease (CKD) that may reduce patients’ health-related quality of life (HRQoL). This study explored the experience and knowledge of patients with CKD, with and without anemia, in China.
Methods: A quantitative online survey was administered to 500 consenting Chinese patient volunteers aged ≥ 18 years with self-reported CKD, with or without anemia, between August 29, and September 17, 2018. Patients with cancer were excluded. The 27-question survey explored knowledge of anemia, HRQoL, anemia management, and interactions with healthcare providers.
Results: Of 456 evaluable patients, 148 (32.5%) reported having anemia and 262 (57.5%) did not. Knowledge of anemia and its symptoms varied, and approximately half of all patients did not know their hemoglobin level. Patients with anemia expressed an adverse impact of anemia on HRQoL, most commonly lack of energy (65.5%), sadness/depression (54.1%), and feeling ill (50.0%). The most frequently reported treatments among these patients were dietary advice (68.9%), iron supplements (63.5%), and oral medications (53.4%). Although 89.2% of patients with anemia trusted their healthcare providers above other information sources, only 29.0% reported seeking information from them; this was despite 92.6% reporting wanting further information and support about managing conditions like anemia.
Conclusion: Our findings suggest that patients with CKD, both with and without anemia, would benefit from increased awareness of anemia and more in-depth discussions with healthcare providers in order to facilitate better management of CKD and optimization of treatment plans.
Keywords: anemia, chronic kidney disease, survey, patient perspectives, China
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