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Ulcerative colitis six years after colon cancer: only a coincidence?

Authors Sakellakis M, Makatsoris T, Gkermpesi M, Peroukidis S, Kalofonos H

Received 5 February 2014

Accepted for publication 11 March 2014

Published 29 April 2014 Volume 2014:7 Pages 85—88

DOI https://doi.org/10.2147/IMCRJ.S61950

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3


Minas Sakellakis,1 Thomas Makatsoris,1 Maria Gkermpesi,2 Stavros Peroukidis,1 Haralabos Kalofonos1

1Division of Oncology, Department of Medicine, 2Department of Pathology, University, Hospital of Patras, Patras, Greece

Abstract: The association between inflammatory bowel disease and colorectal cancer is well known. Ulcerative colitis is a risk factor for the development of colorectal cancer, and this risk increases with the activity and duration of bowel inflammation. Here we describe the case of a 52-year-old man who developed ulcerative colitis 6 years after the diagnosis and treatment of colon cancer. Although this could be a coincidence, there could be additional possibilities, like pre-existence of quiescent colitis, late effect of therapy, or maybe the existence of common pathogenetic factors contributing to the development of ulcerative colitis and colorectal cancer.

Keywords: ulcerative, colitis, colorectal, cancer, inflammation

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