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Treatment options for hypertension in high-risk patients

Authors Tsai W

Published 9 March 2011 Volume 2011:7 Pages 137—141

DOI https://doi.org/10.2147/VHRM.S11235

Review by Single-blind

Peer reviewer comments 4


Wei-Chuan Tsai
Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan

Abstract: Patients are considered to be at high risk of cardiovascular events if they have diabetes, chronic kidney disease, stroke, established coronary artery disease, or a coronary artery disease equivalent. Blood pressure-lowering therapy has been shown to reduce cardiovascular events in these patients significantly. Identification of high-risk patients by global risk evaluation is recommended for every hypertensive patient. Treatment of hypertension in high-risk patients with an angiotensin-converting enzyme inhibitor or an angiotensin receptor antagonist, with or without addition of a dihydropyridine calcium channel antagonist, is a reasonable approach based on current clinical trials.


Keywords: hypertension, high-risk, antihypertensive agent

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