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Treatment of recurrent myopic macular hole using membrane of plasma rich in growth factors

Authors Sánchez-Ávila RM, Fernández-Vega González Á, Fernández-Vega Sanz Á, Merayo-Lloves J

Received 6 April 2018

Accepted for publication 4 June 2019

Published 12 July 2019 Volume 2019:12 Pages 229—233

DOI https://doi.org/10.2147/IMCRJ.S170329

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Ms Justinn Cochran

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Ronald M Sánchez-Ávila, Álvaro Fernández-Vega González, Álvaro Fernández-Vega Sanz, Jesús Merayo-Lloves

University Institute Fernández-Vega, Ophthalmological Research Foundation, Oviedo, Spain

Purpose: To describe the case of a patient with a recurrent large myopic macular hole (MH), who was successfully treated with a plasma rich in growth factors (PRGF) membrane.
Case Report: A 71-year-old patient presented a myopic MH in his right eye. One month later, pars plana vitrectomy with internal limiting membrane (ILM) peeling was performed, achieving closure of the MH. Three months later a recurrence was observed (700 μm) without visual acuity (VA) improvement. A new surgery was carried out placing an autologous PRGF-membrane into the MH, and performing a fluid-gas exchange at the end of the surgery. After two months of follow-up, the MH was completely closed, obtaining the anatomic recovery of the foveal depression, and improving the VA to 0.1. No adverse reactions were associated with the use of PRGF and there were no new recurrences of the MH in a follow-up period of six months.
Conclusion: The use of PRGF-membrane can be used as adjunctive therapy in the surgical repair of recurrent large myopic MHs, thus improving anatomic and visual outcomes.

Keywords: myopic macular hole, plasma rich in growth factors, PRGF, retinal surgery, macular hole


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