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Treatment Of Pain In Wounds With A Topical Long Acting Lidocaine Gel

Authors Treadwell T, Walker D, Nicholson BJ, Taylor M, Alur H

Received 22 July 2019

Accepted for publication 30 October 2019

Published 27 November 2019 Volume 2019:6 Pages 117—121


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Prof. Dr. Marco Romanelli

Terry Treadwell,1 Donna Walker,1 BJ Nicholson,1 Maggie Taylor,1 Hemant Alur2

1Institute for Advanced Wound Care, Montgomery, Alabama, USA; 2MilanaPharm, Montgomery, Alabama, USA

Correspondence: Terry Treadwell
Institute for Advanced Wound Care, 2167 Normandie Dr, Montgomery, AL 36111, USA
Tel +1 334 286 3444
Fax +1 334 286 3450

Abstract: The treatment of patients with chronic wounds and pain can be frustrating and filled with potential for medication abuse and addiction. In an attempt to improve the management of this chronic wound pain, a gel containing 4% lidocaine in TRI-726 matrix (lidocaine gel) was evaluated in 33 patients with various types chronic painful wounds. In this weeklong study, the new lidocaine gel was applied once on day 0 and patients recorded their perceived pain level for the next 7 days. Mean reported pain scores and pain intensity difference (PID) were statistically significantly lower on days 1–4 compared to day 0 and days 5–7. This new lidocaine gel was effective in reducing the pain in the majority of patients for multiple days after one application. Further studies are warranted to see if long-term use will reduce the amount of pain medication prescribed in this group of patients.

Keywords: topical lidocaine, painful chronic wounds, PID, TRI-726, abuse, addiction

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