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Transplant surgery and the obese patient: special considerations

Authors Mohan P, Kadian M, Srinivas T

Received 13 March 2015

Accepted for publication 18 August 2015

Published 4 December 2015 Volume 2015:7 Pages 71—81

DOI https://doi.org/10.2147/TRRM.S64014

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Qing Yi

Prince Mohan, Manish Kadian, Titte R Srinivas

Division of Nephrology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA


Abstract: Perhaps as a consequence of increased obesity in the general population, the likelihood of obese patients receiving kidney transplants has more than doubled. Obesity confers increased risk for graft loss and death among renal transplant recipients. However, the relationship of changes in body weight and composition to outcome on the transplant waitlist and posttransplantation are not straightforward. Strategies to manage weight in the waitlisted and post-kidney transplantation patient must be performed in the context of a multidisciplinary approach and individualized to risk factors in particular patients. While retrospective studies offer considerable insight into the relationship between obesity and kidney transplant outcome, causal inferences must be made with great caution.

Keywords: kidney transplant, obesity, delayed graft function, new onset diabetes after transplant, transplant outcomes

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