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Traditional Chinese Medicine Jiuwei Zhenxin Granules in Treating Depression: An Overview

Authors Wang J, Wu X

Received 22 July 2020

Accepted for publication 7 September 2020

Published 2 October 2020 Volume 2020:16 Pages 2237—2255

DOI https://doi.org/10.2147/NDT.S273324

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Yuping Ning


Jing Wang, Xingmao Wu

Department of Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

Correspondence: Xingmao Wu
Department of Critical Care Medicine, Shengjing Hospital of China Medical University, Heping District, Shenyang, Liaoning 110004, People’s Republic of China
Tel/ Fax +86 24 18940251899
Email cmu_xingmaowu@sina.com

Abstract: Depression is known as “Yu Zheng” in traditional Chinese medicine (TCM). Jiuwei Zhenxin granules (JZG) is a type of TCM. According to TCM theory, it nourishes the heart and spleen, tonifies Qi, and tranquilizes the spirit, and may also has effects in the treatment of depression. Here, we systematically reviewed recent basic and clinical experimental studies of JZG and depression, including studies of the pharmacological mechanisms, active ingredients, and clinical applications of JZG in depression treatment. This review will deepen our understanding of the pharmacological mechanisms, drug interactions, and clinical applications of TCM prescriptions and provide a basis for the development of new drugs in the treatment of depression.

Keywords: Jiuwei Zhenxin granules, depression, Yu Zheng, pharmacological, effective substance

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