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The worldwide epidemiology of acute rheumatic fever and rheumatic heart disease

Authors Michael D Seckeler, Tracey R Hoke

Published 22 February 2011 Volume 2011:3(1) Pages 67—84

DOI https://doi.org/10.2147/CLEP.S12977

Review by Single-blind

Peer reviewer comments 2

Michael D Seckeler, Tracey R Hoke
Department of Pediatrics, Division of Cardiology, University of Virginia, Charlottesville, VA, USA

Abstract: Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are significant public health concerns around the world. Despite decreasing incidence, there is still a significant disease burden, especially in developing nations. This review provides background on the history of ARF, its pathology and treatment, and the current reported worldwide incidence of ARF and prevalence of RHD.

Keywords: rheumatic fever, rheumatic heart disease, group A streptococcus, epidemiology
 

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