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The role of the monoamine oxidase A gene in moderating the response to adversity and associated antisocial behavior: a review

Authors Buades-Rotger M, Gallardo-Pujol D

Received 9 November 2013

Accepted for publication 1 May 2014

Published 30 July 2014 Volume 2014:7 Pages 185—200

DOI https://doi.org/10.2147/PRBM.S40458

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2


Macià Buades-Rotger,1,2 David Gallardo-Pujol1,3

1Department of Personality, Faculty of Psychology, University of Barcelona, Barcelona, Spain; 2Department of Neurology, University of Lübeck, Lübeck, Germany; 3Institute for Brain, Cognition and Behavior (IR3C), University of Barcelona, Barcelona, Spain

Abstract: Hereditary factors are increasingly attracting the interest of behavioral scientists and practitioners. Our aim in the present article is to introduce some state-of-the-art topics in behavioral genetics, as well as selected findings in the field, in order to illustrate how genetic makeup can modulate the impact of environmental factors. We focus on the most-studied polymorphism to date for antisocial responses to adversity: the monoamine oxidase A gene. Advances, caveats, and promises of current research are reviewed. We also discuss implications for the use of genetic information in applied settings.

Keywords: behavioral genetics, antisocial behaviors, monoamine oxidase A

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