The potential clinical applications and prospects of microRNAs in lung cancer
Ying Gao,1 Fei Gao,2,* Jin-lu Ma,1,* Wen-ze Sun,1 Li-ping Song1
1Department of Radiotherapy Oncology, First Affiliated Hospital of Medical College of Xi'an Jiaotong University, 2Department of Neurology, First Affiliated Hospital of Xi'an Medical University, Xi'an, People's Republic of China
*These authors contributed equally to this work
Abstract: Lung cancer is the major cause of cancer deaths worldwide due to its late diagnosis and poor outcome. Understanding genomic medicine may widen our vision into the oncogenesis of lung cancer and may open the door to improvements in the clinical management of lung cancer. It is well known that almost half of all genes are regulated by microRNAs (miRNAs). This review focuses on the role of miRNAs in lung cancer and also touches on the value of miRNA-based novel therapies for lung cancers.
Keywords: microRNA, lung cancer, biomarker, chemotherapy, radiotherapy
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