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The First Report of Triple Advanced Synchronous Cancer: Bladder Transitional Cell Carcinoma and Clinically Silent Adenocarcinoma of Prostate and Colon

Authors Ghaed MA, Jahanshahi F, Maleki F

Received 20 May 2019

Accepted for publication 16 November 2019

Published 2 December 2019 Volume 2019:12 Pages 373—377

DOI https://doi.org/10.2147/IMCRJ.S216410

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Melinda Thomas

Peer reviewer comments 3

Editor who approved publication: Professor Ronald Prineas


Mohammad Ali Ghaed,1 Fatemeh Jahanshahi,2 Farid Maleki3

1Department of Urology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran; 2Student Research Committee, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran; 3Department of Surgery, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran

Correspondence: Fatemeh Jahanshahi
Rasoul Akram Hospital, Niayesh Ave., Sattarkhan Street, Tehran, Iran
Tel +98 9124801231
Fax +98 21 64352353
Email Fjahanshahi.researcher@gmail.com

Abstract: Multiple synchronous malignancies are believed to be quite rare and their diagnosis and treatment are very challenging for physicians. Co-presence of synchronous bladder and prostate cancers in an elderly individual is not uncommon; however, the simultaneous occurrence of the third cancer – colon cancer – is extremely outlandish. In the present study, the case of an 82-year-old man with a complaint of hematuria is reported who was eventually diagnosed with three synchronous cancers: stage-3 transitional cell carcinoma of the bladder, stage-4 prostate mucinous adenocarcinoma, and stage-3 glandular adenocarcinoma of the colon. The patient underwent total colectomy and radical cystoprostatectomy followed by chemotherapy and radiotherapy. The 2-year follow-up showed promising results with no major complications and the patient’s general condition was satisfactory. Although synchronous cancers are not so common, they should not be disregarded in elderly patients especially in those with multiple symptoms.

Keywords: adenocarcinoma, synchronous, cancer, carcinoma, prostate, colon

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