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The effects of electroconvulsive therapy on tardive dystonia or dyskinesia induced by psychotropic medication: a retrospective study

Authors Yasui-Furukori N, Kikuchi A, Katagai H, Kaneko S, Nakamura K

Received 15 February 2014

Accepted for publication 16 April 2014

Published 3 July 2014 Volume 2014:10 Pages 1209—1212

DOI https://doi.org/10.2147/NDT.S62490

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Norio Yasui-Furukori,1 Atsuhiro Kikuchi,1 Hiroshi Katagai,1,2 Sunao Kaneko1

1Department of Neuropsychiatry, Hirosaki University School of Medicine, 2Department of Neuropsychiatry, Hirosaki-Aiseikai Hospital, Hirosaki, Japan

Background: Tardive dystonia and dyskinesia are potentially irreversible neurological syndromes. Successful electroconvulsive treatment (ECT) has been reported by multiple sources; however, the existing retrospective reviews and open prospective trials provide little information on the response rate.
Methods: Eighteen consecutive patients with tardive dystonia or dyskinesia received a standard course of ECT to treat abnormal movement. The severity of the tardive dystonia and dyskinesia was evaluated using the Abnormal Involuntary Movement Scale (AIMS) before and after the course of ECT. The patients who displayed a greater than 50% improvement in the AIMS score were classified as the responders.
Results: The mean AIMS score decreased from 19.1±4.7 to 9.6±4.2. There were seven responders among the 18 patients, which yielded a 39% response rate.
Conclusion: ECT has a moderate but significant effect on tardive dystonia and dyskinesia.

Keywords: tardive dystonia, tardive diskinesia, ECT, medication

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