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The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore
Authors Ochi H, Tan LC, Oon HH
Received 11 March 2017
Accepted for publication 3 August 2017
Published 18 January 2018 Volume 2018:11 Pages 37—39
DOI https://doi.org/10.2147/CCID.S136730
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 2
Editor who approved publication: Dr Jeffrey Weinberg
Harumi Ochi, Lixian Chris Tan, Hazel H Oon
Department of Dermatology, National Skin Centre, Singapore
Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore.
Keywords: hidradenitis suppurativa, combination therapy, clindamycin, rifampicin
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