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The complementary benefit of anterior segment optical coherence tomography in penetrating keratoplasty

Authors Yenerel NM, Kucumen RB, Gorgun E

Received 29 March 2013

Accepted for publication 3 May 2013

Published 23 July 2013 Volume 2013:7 Pages 1515—1523

DOI https://doi.org/10.2147/OPTH.S45904

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5

Nursal Melda Yenerel,1 Raciha Beril Kucumen,2 Ebru Gorgun3

1Haydarpasa Numune Research and Training Hospital, Istanbul, Turkey; 2Yeditepe University Medical Faculty, Department of Ophthalmology, Istanbul, Turkey; 3Dunya Goz Eye Hospital, Istanbul, Turkey

Purpose: To evaluate the utility of anterior segment optical coherence tomography (AS-OCT) assessment in the pre- and postsurgical management of full-thickness corneal grafts.
Methods: Seventy eyes of 58 patients who had penetrating keratoplasty were included in the study. High resolution AS-OCT scans of the cornea and the anterior segment were performed before and after transplantation in 17 eyes with the VisanteTM optical coherence tomography. Fifty-three eyes were examined in the late postoperative period.
Results: The mean follow-up was 4.3 years (range, 1–15 years). Six different graft–host junctions were identified. Three patients with graft rejection, four patients with anterior synechia, and three patients with corneal ulcer were evaluated. Preoperative evaluation of eyes with semiopaque and totally opaque corneas revealed important information about anterior segment structures additional to slit-lamp findings.
Conclusion: AS-OCT is a useful complementary tool for the evaluation of penetrating corneal transplantation surgery and in the management of its postoperative complications.

Keywords: anterior segment optical coherence tomography, imaging techniques, penetrating keratoplasty

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