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The comorbidity of bipolar disorder, diabetes mellitus, and autoimmune hypothyroidism in an adult woman with Turner’s syndrome: a case report

Authors Li J, Hong X, Xu H

Received 5 April 2017

Accepted for publication 10 July 2017

Published 18 September 2017 Volume 2017:13 Pages 2425—2428


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Professor Wai Kwong Tang

Jinling Li, Xiaohong Hong, Haiyun Xu

The Mental Health Center, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China

Abstract: Turner’s syndrome (TS) is the most common sex chromosome abnormality in females and characterized with short stature and ovarian dysgenesis. Patients with TS may also present many other physical diseases and mental disorders. In this case report, we present a 49-year-old woman with TS, who also met criteria for bipolar disorder, type 2 diabetes mellitus, and autoimmune hypothyroidism. The patient was admitted to the mental health center for depressive symptoms in 1991 and was misdiagnosed as hypopituitarism, which was not corrected until 2005 when her karyotype of 45, X/46, X, i(Xq) was identified. Due to the misdiagnosis and other specific reasons, the patient missed the optimal time for hormone replacement therapy.

Keywords: Turner’s syndrome, bipolar disorder, karyotype, comorbidity

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