Teneligliptin and “Thorough QTc study”: thorough enough?
Department of Endocrinology, Nightingale Hospital, Kolkata, India
I read with interest the “Thorough QTc study” with teneligliptin by Erande et al.1 It came as a surprise to me that the basic structure required to conduct such a trial as per the ICH E14 recommendations for the industry was not followed.2 The recommended design to conduct such a trial was not universally followed (Table1).
View the original paper by Erande and colleagues
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