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Technetium-99m tetrofosmin: Use for myocardial perfusion imaging in the detection of coronary artery disease

Authors D'Arceuil H

Published 13 August 2010 Volume 2010:3 Pages 1—10

DOI https://doi.org/10.2147/RMI.S7565

Review by Single-blind

Peer reviewer comments 3


Helen Erica D’Arceuil

Department of Radiology, Stanford University School of Medicine, California, USA

Abstract: Technetium-99m tetrofosmin is a radioactive tracer which is designed for ­myocardial perfusion imaging. Differential tracer uptake allows discrimination between normal and ischemic myocardium. Technetium-99m tetrofosmin has shown excellent utility as a safe, cost-effective, and technically sound agent for use in the diagnosis of coronary artery disease. This paper provides an overview of the available literature on clinical applications of technetium-99m tetrofosmin, and shows how this tracer has gained widespread acceptance as a diagnostic aid since its inception approximately 17 years ago. The various cardiac imaging modalities and imaging protocols which have employed this agent are also briefly reviewed.

Keywords: technetium-99m tetrofosmin, myocardial, viability, imaging

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