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Takotsubo cardiomyopathy: etiology, diagnosis, and optimal management

Authors Wan S, Liang J

Received 17 June 2014

Accepted for publication 24 July 2014

Published 29 October 2014 Volume 2014:5 Pages 297—303

DOI https://doi.org/10.2147/RRCC.S46021

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Editor who approved publication: Dr Richard Kones

Siu-Hin Wan, Jackson J Liang

Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN, USA


Abstract: Takotsubo cardiomyopathy, also known as stress-induced cardiomyopathy or apical ballooning syndrome, is a condition of stress-induced apical hypokinesis in the setting of a preserved basal segment. It has become increasingly recognized and described. While it can mimic the presentation of an acute myocardial infarction, it is a transient phenomenon, and ventricular systolic function typically recovers completely. We review the relevant literature over the past 2 decades regarding the pathophysiology, diagnosis, epidemiology, management, and prognosis of this condition.

Keywords: apical ballooning syndrome, takotsubo cardiomyopathy, stress-induced cardiomyopathy, myocardial infarction, heart failure

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