Systemic lupus erythematosus flare triggered by a mosquito bite: the first case report
Received 11 January 2019
Accepted for publication 28 February 2019
Published 13 May 2019 Volume 2019:11 Pages 117—119
Checked for plagiarism Yes
Review by Single-blind
Peer reviewers approved by Dr Colin Mak
Peer reviewer comments 3
Editor who approved publication: Professor Chuan-Ju Liu
Vadood Javadi Parvaneh, Mohsen Jari, Sheri Motahari, Khosro Rahmani, Reza Shiari
Department of Pediatric Rheumatology, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide, various, and sometimes deceptive clinical and serological manifestations. Environmental factors such as ultraviolet radiation, viral infections, drugs, hormones, and chemicals could trigger SLE flares in genetically predisposed patients.
Case report: We presented a 13-year-old girl with the first presentation of systemic lupus erythematosus triggered by a mosquito bite. She presented with a malar rash started after a mosquito bite on her left cheek. She had oral ulcers, photosensitivity, lymphopenia, proteinuria, and positive serologic tests for SLE. Renal biopsy revealed class II lupus nephritis.
Conclusion: Environmental factors can trigger the onset of SLE in genetically susceptible cases. Besides microbial agents, UV radiation, hormones, drugs, emotional stresses, immunization, and chemicals are some of the published examples. We presented a case with a mosquito bite as the possible environmental trigger.
Keywords: mosquito bite, systemic lupus erythematosus, children, pediatrics, etiology, case report
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