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Systemic lupus erythematosus flare triggered by a mosquito bite: the first case report

Authors Javadi Parvaneh V, Jari M, Motahari S, Rahmani K, Shiari R

Received 11 January 2019

Accepted for publication 28 February 2019

Published 13 May 2019 Volume 2019:11 Pages 117—119


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Professor Chuan-Ju Liu

Video abstract presented by Vadood Javadi Parvaneh.

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Vadood Javadi Parvaneh, Mohsen Jari, Sheri Motahari, Khosro Rahmani, Reza Shiari

Department of Pediatric Rheumatology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Introduction: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a wide, various, and sometimes deceptive clinical and serological manifestations. Environmental factors such as ultraviolet radiation, viral infections, drugs, hormones, and chemicals could trigger SLE flares in genetically predisposed patients.
Case report: We presented a 13-year-old girl with the first presentation of systemic lupus erythematosus triggered by a mosquito bite. She presented with a malar rash started after a mosquito bite on her left cheek. She had oral ulcers, photosensitivity, lymphopenia, proteinuria, and positive serologic tests for SLE. Renal biopsy revealed class II lupus nephritis.
Conclusion: Environmental factors can trigger the onset of SLE in genetically susceptible cases. Besides microbial agents, UV radiation, hormones, drugs, emotional stresses, immunization, and chemicals are some of the published examples. We presented a case with a mosquito bite as the possible environmental trigger.

Keywords: mosquito bite, systemic lupus erythematosus, children, pediatrics, etiology, case report

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