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Systematic Review of Studies Using Conjoint Analysis Techniques to Investigate Patients’ Preferences Regarding Osteoarthritis Treatment

Authors Al-Omari B, McMeekin P, Bate A

Received 17 October 2020

Accepted for publication 14 January 2021

Published 3 February 2021 Volume 2021:15 Pages 197—211


Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Johnny Chen

Basem Al-Omari,1 Peter McMeekin,2 Angela Bate2

1College of Medicine and Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates; 2School of Health and Life Science, University of Northumbria, Newcastle-Upon-Tyne, UK

Correspondence: Basem Al-Omari
College of Medicine and Health Sciences, Khalifa University, PO Box 127788, Abu Dhabi, United Arab Emirates
Tel +971 28109807

Background: The use of conjoint analysis (CA) to elicit patients’ preferences for osteoarthritis (OA) treatment has the potential to contribute to tailoring treatments and enhancing patients’ compliance and adherence. This review’s main aim was to identify and summarise the evidence that used conjoint analysis techniques to quantify patient preferences for OA treatments.
Methods: A comprehensive search strategy was conducted using electronic databases and hand reference checks. Databases were searched from their inception until 10th June 2019. All OA and CA related terms were used to conduct the search. The authors reviewed the papers and used the International Society of Pharmacoeconomics and Outcomes Research (ISPOR) checklist to assess the quality of the included studies.
Results: The search identified 534 records. Sixteen records were selected for full-text review and quality assessment and all were included in the narrative data synthesis. All included studies suggested that the severity of symptoms influenced the patients’ preference for OA treatment. All included studies recognised CA as a useful method to investigate patients’ preferences concerning OA treatment.
Conclusion: Patients preference for OA treatment is driven by the severity of patients’ symptoms and the desire to avoid treatment side effects and CA is a useful tool to investigate patients’ preferences for OA treatment.

Keywords: patient preferences, osteoarthritis, conjoint analysis

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