Systematic review and meta-analysis of cancer studies evaluating diagnostic test accuracy and prognostic values: approaches to improve clinical interpretation of results
Rama Jayaraj,1 Chellan Kumarasamy2
1College of Health and Human Sciences, Charles Darwin University, Ellengowan Drive, Darwin, Northern Territory, Australia; 2The University of Adelaide, North Terrace Campus, Adelaide, South Australia, Australia
The article, “Diagnostic and prognostic value of microRNAs in cholangiocarcinoma: a systematic review and meta-analysis”, published by Sun et al in the Cancer Management and Research journal, has caught our attention.1 There are only few studies available on the subject of prognostic and diagnostic markers in cholangiocarcinoma, when compared with the literature available on other forms of cancer. For this reason, we believe that Sun et al’s study can be a valid reference point for future studies in this field. However, we have a few valid suggestions and approaches on regarding the article, which may help improve its quality, as well as its capability to inform future research.
View original paper by Sun and colleagues.