Back to Journals » International Journal of Women's Health » Volume 10

Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report

Authors Guida M, Maffucci D, Iannuzzi G, Giordano M, Luciano G, Di Benedetto L, Cantarella R, Rescigno A, Giugliano L

Received 1 August 2018

Accepted for publication 12 October 2018

Published 21 November 2018 Volume 2018:10 Pages 745—750

DOI https://doi.org/10.2147/IJWH.S182131

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Cristina Weinberg

Peer reviewer comments 2

Editor who approved publication: Professor Elie Al-Chaer


M Guida,1 D Maffucci,1 G Iannuzzi,1 M Giordano,1 G Luciano,1 L Di Benedetto,2 R Cantarella,3 A Rescigno,3 L Giugliano1

1Università degli studi di Salerno – Dipartimento di Medicina, Chirurgia e Odontoiatria “Scuola Medica Salernitana”, Salerno, Italy; 2Università degli studi di Roma “La Sapienza” – Dipartimento di Scienze Medico-Chirurgiche e di Medicina Traslazionale – Facoltà di Medicina e Psicologia Azienda Ospedaliera Sant’ Andrea, Rome, Italy; 3Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi D’Aragona, Salerno, Italy

Objective: This paper reports on a rare case of pregnancy after uterine artery embolization (UAE) for uterine arteriovenous malformation (AVM). Debate exists about persistence of fertility in women after UAE. Adverse effects of this technique can modify both uterine echostructure, inducing necrosis and infarction, endometrial atrophy and uterine artery rupture, and ovarian reserve, causing persistent amenorrhea. Ovarian reserve appears to be affected by UAE in premenopausal women. However, younger ovaries (according to biological ovarian age) exhibit a greater capacity for recovery after ovarian damage. Therefore, larger studies are needed for more conclusive results.
Case report: A 28-year-old woman was admitted to our department due to life-threatening uterine bleeding, resulting in tachycardia, pallor, and sweating. The patient came with a history of two spontaneous miscarriages. After sonography and computed tomography, AVMs were identified at uterine fundus and anterior wall.
Conclusion: The pathogenesis of infertility after UAE is not yet known. The peculiarity of this case was that, only few months later, the patient became pregnant and gave birth to a live fetus at 37 weeks with cesarean delivery.

Keywords: uterine artery embolization, fertility, uterine arteriovenous malformation, pregnancy, angiography

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]