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Spontaneous internal jugular vein thrombosis as primary presentation of antiphospholipid syndrome: case report

Authors Al-Zoubi NA

Received 4 April 2018

Accepted for publication 10 May 2018

Published 16 July 2018 Volume 2018:14 Pages 153—155

DOI https://doi.org/10.2147/VHRM.S170140

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Naga Venkata Amarnath Kommuri


Nabil A Al-Zoubi

Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan

Introduction: Spontaneous and isolated internal jugular vein (IJV) thrombosis is a rare entity, and atypical localization for venous thromboembolism usually occurs after an oropharyngeal infection, cancer, central venous catheter, and ovarian hyperstimulation syndrome. This report describes a case of spontaneous IJV thrombosis leading to neck pain and swelling as a primary manifestation of antiphospholipid (Hughes) syndrome.
Case presentation: A 44-year-old male with no significant past medical history presented with a 1-week duration of right-sided painful neck swelling. Duplex ultrasound and computed tomography angiogram revealed right IJV thrombosis. Hematology studies were normal apart from positive lupus anticoagulant. The patient was managed conservatively with low molecular weight heparin, antibiotics, and close follow-up.
Conclusion: Acute spontaneous IJV thrombosis as a primary presentation of antiphospholipid syndrome is extremely uncommon. We should be aware of the possibility of this condition in the differential diagnosis and management, as long-term anticoagulation is needed.

Keywords: internal jugular vein, antiphospholipid syndrome, lupus anticoagulant

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