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Spinal Intramedullary Solitary Fibrous Tumor: A Rare and Challenging Diagnosis

Authors Yang C, Xu Y, Liu X

Received 14 September 2019

Accepted for publication 3 December 2019

Published 10 December 2019 Volume 2019:11 Pages 10321—10326


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Beicheng Sun

Chenlong Yang,1 Yulun Xu,2 Xiaoguang Liu1

1Department of Orthopedics, Peking University Third Hospital, Beijing 100191, People’s Republic of China; 2Department of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, People’s Republic of China

Correspondence: Xiaoguang Liu; Yulun Xu Email;

Background: Solitary fibrous tumor (SFT) is a benign neoplasm arising in the soft tissue, which can occur anywhere in the body, while it is predominantly found in the visceral pleura. Spinal SFT is quite uncommon, with limited cases having been reported in the literature; especially, SFT occurring in the intramedullary site is extremely rare.
Case presentation: We present a case of a 35-year-old woman presenting with progressive numbness and weakness in the legs and urinary incontinence. Magnetic resonance imaging (MRI) showed an intramedullary lesion with bright enhancement. A diagnosis of spinal hemangioblastoma was suspected, and thus a three-dimensional computed tomographic angiography reconstruction was requested, which also demonstrated an angiomatous lesion. The tumor was completely resected under neurophysiological monitoring. However, histopathological and immunohistochemical examinations revealed an SFT. No adjuvant radiotherapy or chemotherapy was scheduled. The symptoms were relieved completely, and no recurrence or progression was noted during the follow-up.
Conclusion: Though SFT has been considered similar to malignant hemangiopericytoma and the histological classification has always been controversial, the intramedullary location and benign behavior in the present case add to the current understandings of this extremely rare entity.

Keywords: solitary fibrous tumor, spinal tumor, intramedullary tumor, MRI, CTA, case report

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