Back to Journals » Neuropsychiatric Disease and Treatment » Volume 9

Sodium valproate-induced enuresis in a pediatric bipolar patient

Authors Cheng W, Lin X, Lu D, Luo L

Received 22 August 2013

Accepted for publication 3 September 2013

Published 31 October 2013 Volume 2013:9 Pages 1671—1672

DOI https://doi.org/10.2147/NDT.S53388

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Wentao Cheng,1,* Xiaoling Lin,2,* Dali Lu1

1Department of Pediatric and Geriatric Psychiatry, Fuzhou Neuropsychiatric Hospital, Fuzhou, Fujian, People's Republic of China; 2School of Nursing of Central South University, Changsha, Hunan, People's Republic of China

*These authors contributed equally to this work

Abstract: Sodium valproate (SV) is effective and well tolerated for the treatment of epilepsy and mood disorders. There are several cases of SV-induced enuresis noted in epileptic patients. No alternative medication has been suggested to manage this problem. We present the first case of a pediatric bipolar patient who developed diurnal and nocturnal enuresis during SV therapy. Clinicians should be aware of this side effect, as it has not been reported in nonepileptic patients, and it may be detrimental to treatment adherence.

Keywords: sodium valproate, enuresis, bipolar disorder

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]