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Simultaneous Infection of the Skin Surface and Dermal Tissue with Two Different Fungus Mimicking Pyoderma Gangrenosum: A Case Report

Authors Jia QY, Song YG, Li XQ, Mu ZL, Li RY, Li HM

Received 24 October 2020

Accepted for publication 26 January 2021

Published 15 February 2021 Volume 2021:14 Pages 163—167

DOI https://doi.org/10.2147/CCID.S286582

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 2

Editor who approved publication: Dr Jeffrey Weinberg


Qiu-Yu Jia,1 Ying-Gai Song,2 Xiang-Qian Li,1 Zhang-Lei Mu,1 Ruo-Yu Li,2 Hou-Min Li1

1Department of Dermatology, Peking University People’s Hospital, Beijing, People’s Republic of China; 2Department of Dermatology, Peking University the First Hospital, Beijing, People’s Republic of China

Correspondence: Hou-Min Li
Department of Dermatology, Peking University People’s Hospital, No. 11 Xizhimen South Street, Xicheng District, Beijing, 100044, People’s Republic of China
Tel +86 (424) 390-2625
Email lhoumin@sina.cn

Abstract: Mucormycosis is an opportunistic fungal infection driven by subphylum Mucormycotina. Cutaneous mucormycosis is the third most common presentation of mucormycosis, and its characterized presentation is an indurated plaque that rapidly evolves to necrosis. Trichophyton rubrum is one of the most common dermatophytes that mainly cause superficial infections and seldom induce deep infections. The present report presents a case of cutaneous fungal infection, in which two kinds of fungus were isolated, and the skin lesion mimicked pyoderma gangrenosum. Trichophyton rubrum was isolated from the crust and hyphae of subphylum Mucormycotina were found in dermal tissue. The irregular systemic and topical use of steroid therapy is the possible cause of the mixed fungal infection in this patient, suggesting the importance of regular steroid therapy.

Keywords: cutaneous mucormycosis, Trichophyton rubrum infection, cutaneous infection, lower leg, steroid therapy

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