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Severe panuveitis in neuro-Behçet’s disease in Malaysia: a case series

Authors Othman K, Liza-Sharmini AT, Ibrahim M, Tharakan J, Yanai R, Zunaina E

Received 8 September 2016

Accepted for publication 12 November 2016

Published 7 February 2017 Volume 2017:10 Pages 35—40

DOI https://doi.org/10.2147/IMCRJ.S121863

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Khairuddin Othman,1 Ahmad Tajudin Liza-Sharmini,1 Mohtar Ibrahim,1 John Tharakan,2 Ryoji Yanai,3 Embong Zunaina1

1Department of Ophthalmology, 2Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia; 3Department of Ophthalmology, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan

Abstract:
Behçet’s disease (BD) is a multisystemic disease that is very rare in Malaysia. About 5% of patients develop central nervous system involvement, termed neuro-Behçet’s. Neuro-Behçet’s is one of the most serious causes of long-term morbidity and mortality. We report two cases of neuro-Behçet’s associated with uveitis (ocular BD) highlighting the clinical presentation, diagnostic measurement, and therapeutic management of these cases.

Keywords:
Behçet’s disease, Behçet’s syndrome, parenchymal neuro-Behçet’s, uveitis

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