Back to Journals » Vascular Health and Risk Management » Volume 9

Serum calcium levels are not associated with coronary heart disease

Authors Jin Y, He L, Wang Q, Chen Y, Ren X, Tang H, Song X, Ding L, Qi Q, Huang Z, Yu J, Yao Y

Received 29 May 2013

Accepted for publication 17 July 2013

Published 3 September 2013 Volume 2013:9 Pages 517—520


Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Yuelong Jin,* Lianping He,* Quanhai Wang, Yan Chen, Xiaohua Ren, Hui Tang, Xiuli Song, Lingling Ding, Qin Qi, Zhiwei Huang, Jiegen Yu, Yingshui Yao

Department of Preventive Medicine, Wannan Medical College, Wuhu, People's Republic of China

*These authors contributed equally to this work

Background: Numerous studies have reported that low calcium intake is related to a higher prevalence of cardiovascular disease. However, the relationship between serum calcium and coronary heart disease is unclear. The purpose of this study was to compare serum calcium levels in patients with coronary heart disease and those in healthy individuals.
Methods: This retrospective, case-control study conducted in the People's Republic of China comprised 380 cases and 379 controls. Serum calcium levels, blood lipids, and anthropometric measurements were measured in both groups. The Student's unpaired t-test or Chi-square test was used to compare differences between cases and controls. Pearson's partial correlation coefficient was used to determine the association between serum calcium, blood lipids, and blood pressure in both groups.
Results: Our results indicate that the average level of serum calcium in cases was higher than in controls. Serum calcium levels showed no correlation with any parameter except for triglycerides in either group.
Conclusion: Overall, these data suggest that serum calcium has no influence on coronary heart disease or triglyceride levels in the general population.

Keywords: serum calcium, hypertension, blood lipids

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]


Other article by this author:

Investigation on Internet addiction disorder in adolescents in Anhui, People’s Republic of China

Chen Y, Kang Y, Gong W, He L, Jin Y, Zhu X, Yao Y

Neuropsychiatric Disease and Treatment 2016, 12:2233-2236

Published Date: 29 August 2016

Readers of this article also read:

Spanish translation, cross-cultural adaptation, and validation of the Questionnaire for Diabetes-Related Foot Disease (Q-DFD)

Castillo-Tandazo W, Flores-Fortty A, Feraud L, Tettamanti D

Vascular Health and Risk Management 2013, 9:501-508

Published Date: 28 August 2013

Current status of NADPH oxidase research in cardiovascular pharmacology

Rodiño-Janeiro BK, Paradela-Dobarro B, Castiñeiras-Landeira MI, Raposeiras-Roubín S, González-Juanatey JR, Álvarez E

Vascular Health and Risk Management 2013, 9:401-428

Published Date: 25 July 2013

The COSEHC™ Global Vascular Risk Management quality improvement program: first follow-up report

Ferrario CM, Joyner J, Colby C, Exuzides A, Moore M, Simmons D, Bestermann Jr W, Frech-Tamas F

Vascular Health and Risk Management 2013, 9:391-400

Published Date: 22 July 2013

Statins in heart failure: do we need another trial?

Bonsu KO, Kadirvelu A, Reidpath DD

Vascular Health and Risk Management 2013, 9:303-319

Published Date: 17 June 2013

Heel-rise test in the assessment of individuals with peripheral arterial occlusive disease

Monteiro DP, Britto RR, Lages AC, Basílio ML, Pires MC, Carvalho ML, Procópio RJ, Pereira DA

Vascular Health and Risk Management 2013, 9:29-35

Published Date: 23 January 2013

Atrial fibrillation and thromboprophylaxis in heart failure: the need for patient-centered approaches to address adherence

Ferguson C, Inglis SC, Newton PJ, Middleton S, Macdonald PS, Davidson PM

Vascular Health and Risk Management 2013, 9:3-11

Published Date: 17 January 2013

Patterns of warfarin use and subsequent outcomes in atrial fibrillation in primary care practices

Ewen E, Zhang Z, Simon TA, Kolm P, Liu X, Weintraub WS

Vascular Health and Risk Management 2012, 8:587-598

Published Date: 19 October 2012

Prevalence and risk factors associated with peripheral artery disease in elderly patients undergoing peritoneal dialysis

Kuang DW, Li CL, Kuok UI, Cheung K, Lio WI, Xin J

Vascular Health and Risk Management 2012, 8:581-586

Published Date: 19 October 2012

The prevention and regression of atherosclerotic plaques: emerging treatments

Kalanuria AA, Nyquist P, Ling G

Vascular Health and Risk Management 2012, 8:549-561

Published Date: 25 September 2012

Nitric oxide and coronary vascular endothelium adaptations in hypertension

Andrew S Levy, Justin CS Chung, Jeffrey T Kroetsch, et al

Vascular Health and Risk Management 2009, 5:1075-1087

Published Date: 16 December 2009