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Selected luminal mucosal complications of adult celiac disease

Authors Hugh J Freeman

Published 4 February 2009 Volume 2009:2 Pages 9—12

DOI http://dx.doi.org/10.2147/CEG.S4777

Review by Single-blind

Peer reviewer comments 3

Hugh J Freeman

Department of Medicine (Gastroenterology), University of British Columbia, Vancouver, BC, Canada

Abstract: Celiac disease is a gluten-dependent intestinal disorder that appears to be associated with several clinical conditions. Some involve the luminal mucosa of the stomach and intestinal tract and may, occasionally, complicate the course of celiac disease. Collagenous colitis has been associated with celiac disease and may lead to chronic diarrhea. Conversely, some of these clinical disorders that involve the luminal mucosa of the stomach and intestine may represent the initial clinical presentation of celiac disease. These disorders should be considered in patients with celiac disease who develop recurrent or refractory symptoms despite adherence to a strict gluten-free diet. Detection of collagenous disorders that affect the luminal mucosa of the stomach or intestinal tract may result in recognition of underlying celiac disease.

Keywords: celiac disease, collagenous gastritis, collagenous sprue, collagenous colitis, gluten-free diet

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