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Safety and efficacy of tazarotene foam for the treatment of acne vulgaris

Authors Epstein EL, Gold LS

Received 2 April 2013

Accepted for publication 15 April 2013

Published 14 May 2013 Volume 2013:6 Pages 123—125

DOI https://doi.org/10.2147/CCID.S34054

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 4

Erica L Epstein, Linda Stein Gold

Henry Ford Hospital, Detroit, MI, USA

Background: Tazarotene foam is the first topical retinoid foam approved for the treatment of acne vulgaris.
Objective: To review the safety and efficacy studies of tazarotene foam in the treatment of moderate to severe acne.
Methods: Five Phase I safety studies in normal controls are reviewed and two Phase III safety and efficacy studies in patients with moderate to severe acne are reviewed.
Conclusion: Tazarotene foam, 0.1% was effective in the treatment of moderate to severe acne vulgaris with an acceptable tolerability profile. This treatment provides a cosmetically favorable alternative for topical retinoid therapy.

Keywords: tazarotene, acne, foam, topical retinoid

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