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Sacral neuromodulation in overactive bladder: a review and current perspectives

Authors Sukhu T, Kennelly MJ, Kurpad R

Received 24 December 2015

Accepted for publication 14 July 2016

Published 26 October 2016 Volume 2016:8 Pages 193—199

DOI https://doi.org/10.2147/RRU.S89544

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Lucy Goodman

Peer reviewer comments 3

Editor who approved publication: Dr Jan Colli


Troy Sukhu,1 Michael J Kennelly,2 Raj Kurpad1

1Department of Urology, University of North Carolina, Chapel Hill, 2Department of Urology, Carolinas Medical Center, Charlotte, NC, USA

Abstract: Overactive bladder (OAB) symptoms of urgency, frequency, and urge incontinence currently affect a substantial portion of the population, especially as age increases. Sacral neuromodulation has become a popular option for refractory OAB symptoms over the past 2 decades. Studies have demonstrated that it is an effective treatment for OAB and urge incontinence as indicated by decreased number of voids, increased bladder capacity, and fewer leakage events. In addition, the effects have proved to be durable to multiple years following implantation. These benefits come at the expense of a high rate of adverse events, although with comparable long-term cost-effectiveness to botulinum toxin A. We aimed to review the literature that demonstrates that sacral neuromodulation continues to be an efficacious treatment for refractory OAB wet and dry patients, with continuously expanding indications.

Keywords: urge incontinence, sacral neuromodulation, overactive bladder, refractory, voiding dysfunction

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