Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 10 » Issue 1

Role of the fixed combination of fluticasone and salmeterol in adult Chinese patients with asthma and COPD

Authors Gao J, Pleasants RA

Received 9 January 2015

Accepted for publication 6 March 2015

Published 15 April 2015 Volume 2015:10(1) Pages 775—789

DOI https://doi.org/10.2147/COPD.S80656

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Richard Russell

Jinming Gao,1 Roy A Pleasants2

1Department of Respiratory Diseases, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University Medical Center, Durham, NC, USA

Abstract: Chronic obstructive pulmonary disease (COPD) and asthma are common airway disorders characterized by chronic airway inflammation and airflow obstruction, and are a leading cause of morbidity and mortality in the People’s Republic of China. These two diseases pose a high economic burden on the family and the whole of society. Despite evidence-based Global Initiative for Chronic Obstructive Lung Disease and Global Initiative for Asthma guidelines being available for the diagnosis and management of COPD and asthma, many of these patients are not properly diagnosed or managed in the People’s Republic of China. The value of combination therapy with inhaled corticosteroids and long-acting β2-agonists has been established in the management of asthma and COPD globally. Combinations of inhaled corticosteroids and long-acting β2-agonists such as fluticasone and salmeterol, have been shown to be effective for improving symptoms, health status, and reducing exacerbations in both diseases. In this review, we discuss the efficacy and safety of this combination therapy from key studies, particularly in the People’s Republic of China.

Keywords: People’s Republic of China, chronic obstructive pulmonary disease, asthma, fluticasone, salmeterol

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]

 

Readers of this article also read:

Caenorhabditis elegans as an alternative in vivo model to determine oral uptake, nanotoxicity, and efficacy of melatonin-loaded lipid-core nanocapsules on paraquat damage

Charão MF, Souto C, Brucker N, Barth A, Jornada DS, Fagundez D, Ávila DS, Eifler-Lima VL, Guterres SS, Pohlmann AR, Garcia SC

International Journal of Nanomedicine 2015, 10:5093-5106

Published Date: 10 August 2015

Home-based pulmonary rehabilitation improves clinical features and systemic inflammation in chronic obstructive pulmonary disease patients

Nascimento ESP, Sampaio LMM, Peixoto-Souza FS, Dias FD, Gomes ELFD, Greiffo FR, Ligeiro de Oliveira AP, Stirbulov R, Vieira RP, Costa D

International Journal of Chronic Obstructive Pulmonary Disease 2015, 10:645-653

Published Date: 23 March 2015

Competitive inhibition of survivin using a cell-permeable recombinant protein induces cancer-specific apoptosis in colon cancer model

Roy K, Kanwar RK, Krishnakumar S, Cheung CH, Kanwar JR

International Journal of Nanomedicine 2015, 10:1019-1043

Published Date: 2 February 2015

Self-assembled micelles of amphiphilic poly(L-phenylalanine)-b-poly(L-serine) polypeptides for tumor-targeted delivery

Zhao ZM, Wang Y, Han J, Wang KL, Yang D, Yang YH, Du Q, Song YJ, Yin XX

International Journal of Nanomedicine 2014, 9:5849-5862

Published Date: 12 December 2014

Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles

Yao JJ, Du YZ, Yuan H, You J, Hu FQ

International Journal of Nanomedicine 2014, 9:2993-3003

Published Date: 18 June 2014

Long-term survival in patients hospitalized for chronic obstructive pulmonary disease: a prospective observational study in the Nordic countries

Gudmundsson G, Ulrik CS, Gislason T, Lindberg E, Brøndum E, Bakke P, Janson C

International Journal of Chronic Obstructive Pulmonary Disease 2012, 7:571-576

Published Date: 14 September 2012