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Review of depot aripiprazole for schizophrenia

Authors Motiwala FB, Siscoe KS, El-Mallakh RS

Received 29 April 2013

Accepted for publication 3 July 2013

Published 13 November 2013 Volume 2013:7 Pages 1181—1187

DOI https://doi.org/10.2147/PPA.S32972

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Farha Bilal Motiwala, Kim Stasia Siscoe, Rif S El-Mallakh

Mood Disorders Research Program, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, KY, USA

Abstract: Improving outcomes in schizophrenia generally requires an improvement in medication adherence. One of the most effective interventions to improve adherence is the use of depot formulations of antipsychotic medications. A new depot aripiprazole formulation for the treatment of schizophrenia will be available soon. A review of all publically available information on depot aripiprazole as of November 2012 was performed. One peer-reviewed study on depot aripiprazole is published, and the remainder of the data were presented at international scientific meetings. Depot aripiprazole appears to be both safe and effective in the long-term treatment of schizophrenia.

Keywords: aripiprazole, schizophrenia, depot, long-acting injectable, psychosis, treatment

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