Back to Journals » Clinical Ophthalmology » Volume 8

Retrobulbar blood flow changes in eyes with diabetic retinopathy a 10 year follow up study

Authors Neudorfer M, Kessner R, Goldenberg D, Lavie A, Kessler A

Received 15 July 2014

Accepted for publication 4 September 2014

Published 21 November 2014 Volume 2014:8 Pages 2325—2332

DOI https://doi.org/10.2147/OPTH.S71158

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 5

Editor who approved publication: Dr Scott Fraser


Meira Neudorfer,1,* Rivka Kessner,1,* Dafna Goldenberg,1 Anat Lavie,1 Ada Kessler2

1Department of Ophthalmology, 2Radiology Ultrasound Unit, Sackler Faculty of Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel

*These authors contributed equally to this work

Purpose: We sought to assess long-term changes in the flow parameters of retrobulbar vessels in diabetic patients.
Methods: The retrobulbar circulation of 138 eyes was evaluated between 1994 and 1995 and 36 eyes were reevaluated between 2004 and 2008 (study group). They were divided into four groups: eyes of diabetic patients without diabetic retinopathy (DR), eyes with nonproliferative DR, eyes with proliferative DR, and eyes of nondiabetic patients (controls). Color Doppler imaging was used to assess the flow velocities in the major retrobulbar vessels. The resistive index (RI) was calculated and compared among the groups and between the two time periods.
Results: RI values of the central retinal artery and posterior ciliary artery had increased in the two non-DR groups and in the nonproliferative DR group, with a surprising decrease measured in eyes with proliferative DR (P= nonsignificant [NS]). Combining the nonproliferative DR and proliferative DR groups resulted in a milder increase of the RI of the posterior ciliary artery (P= NS) and the central retinal artery (P=0.02) in the DR group compared to the other groups.
Conclusion: Our results demonstrate that an increase of the resistance in the retrobulbar vessels, as a part of DR, can lessen over time and may even be reversed.

Keywords: color Doppler imaging, diabetic retinopathy, retrobulbar blood flow

Creative Commons License This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

Download Article [PDF]  View Full Text [HTML][Machine readable]