Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway [Retraction]

Jin Y-L, Xin L-M, Zhou C-C, Ren Y. Onco Targets Ther. 2018;11:8185–8195.

The Editor-in-chief and Publisher of OncoTargets and Therapy wish to retract the published article. Concerns were raised about the possibility of image manipulation in the published article. The alleged image manipulation relates to:

● Figure 2B 786-O 80 μM and Caki-1 80 μM
● Figure 4A Bcl-xl 786-O and Caki-1.

The authors provided the raw data for the requested images; however, the Editor found the provided images were unsatisfactory and doubts were raised about the accuracy of several other figures used in the article. The Editor determined the findings and conclusions presented in the study were no longer supported. The authors institution was contacted for comment but no response was received.

Our decision-making was informed by our policy on publishing ethics and integrity and the COPE guidelines on retraction.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.

This retraction relates to this paper