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Resolute Integrity drug eluting stent safety and efficacy for the treatment of coronary artery disease

Authors Burgos J, Farrag S, Mukherjee D

Received 5 December 2012

Accepted for publication 4 January 2013

Published 22 February 2013 Volume 2013:4 Pages 23—37

DOI https://doi.org/10.2147/RRCC.S31012

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Video abstract presented by Debabrata Mukherjee

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Jose D Burgos, Safa Farrag, Debabrata Mukherjee

Department of Internal Medicine, Paul L Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, TX, USA

Abstract: The need to develop a local antirestenotic mechanism to prevent in-stent thrombosis has driven the development of new generation stents. The Resolute Integrity® stent is a zotarolimus-eluting system with a new BioLinx™ polymer that allows a slower drug elution. Recently available data has shown the clinical efficacy and safety of this stent in randomized and observational studies. The Resolute Integrity stent system has demonstrated noninferiority when compared with other stents and holds the promise to treat more complex coronary lesions.

Keywords: zotarolimus, BioLinx, coronary stenosis, stents, restensosis, stent thrombosis

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