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Relationship between osteopenic syndrome and severity of coronary artery disease detected with coronary angiography and Gensini score in men

Authors Alan B, Akpolat V, Aktan A, Alan S

Received 11 January 2016

Accepted for publication 5 February 2016

Published 24 March 2016 Volume 2016:11 Pages 377—382

DOI https://doi.org/10.2147/CIA.S104036

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Dr Richard Walker

Bircan Alan,1 Veysi Akpolat,2 Adem Aktan,3 Sait Alan3

1Department of Radiology, 2Department of Biophysics, 3Department of Cardiology, Dicle University Medical Faculty, Diyarbakir, Turkey

Background: Many studies have shown that evidence supporting the relationship between low bone mineral density (BMD) and coronary artery disease (CAD) has been increasing. There is a significant increase of myocardial infarction in men with low BMD.
Purpose: We aimed to detect the relationship between BMD and CAD in patients whose CAD was detected with coronary angiography, and its severity and prevalence was detected with Gensini score.
Methods: A total of 55 patients were selected who were found to have single or multiple infarctions through using coronary angiography in the cardiology clinic. The CAD severity was evaluated by calculating the Gensini score. These patients were divided into two groups: mild CAD and severe CAD groups. Femur bone mineral density (FBMD) was measured with dual energy X-ray absorptiometry. T score values were determined to be normal if the values were >-1.0 (n=22, 40%), and osteopenia–osteoporosis (osteopenic syndrome) if the T score values were ≤-1 (n=33, 60%).
Results: The FBMD of severe CAD according to the Gensini risk score was found to be significantly lower. FBMD values in patients decreased as their Gensini scores increased.
Conclusion:
There was a significant relationship between CAD and osteopenic syndrome. FBMD level in men with severe CAD is significantly low when compared with patients who have mild CAD.

Keywords:
osteopenic sydrome, osteoporosis, osteopenia severity of coranary artery disease, bone mineral density

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