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Relationship Between Helicobacter pylori Infection, Serum Vitamin D3 Level and Spontaneous Abortion

Authors Ibrahim HA

Received 24 February 2020

Accepted for publication 2 July 2020

Published 28 July 2020 Volume 2020:13 Pages 469—476

DOI https://doi.org/10.2147/IJGM.S251075

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 2

Editor who approved publication: Dr Scott Fraser


Hadeel Abdulelah Ibrahim

College of Nursing, University of Sulaimani, Kurdistan Region, Republic of Iraq

Correspondence: Hadeel Abdulelah Ibrahim
College of Nursing, University of Sulaimani, Kurdistan Region, Republic of Iraq
Tel +964(0)7703914402
Email hadeel.ibrahim@univsul.edu.iq

Background: The effects of vitamin D3 (VD3) on pregnancy outcomes remain obscure. Thus, this study aims to investigate the relationship between maternal H. pylori infection, low VD3 level, and spontaneous abortion.
Methods: This research is conducted in Shahid Ali Qader Consultant Clinic in Sulaimaniyah city in which 100 women with a history of abortion and 100 women with no history of miscarriage were included. Serum detection of anti-H. pyloriIgG, IgA, and VD3 were done using enzyme-linked immunosorbent assay (ELISA) technique.
Results: The mean of VD3, H. pylori IgG, and IgAin patients and control group cases was determined and analyzed statistically.
Conclusion: H. pylori infection and VD3 play a significant role in early pregnancy loss. Blood group A and O are more prone to spontaneous abortion.

Keywords: miscarriage, bacterial infection, vitamin deficiency, antibody detection, ABO grouping

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