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Relationship between blood pressure levels and adherence to medication in patients with chronic heart failure: How come?

Authors Mohammadi M, Ekman I, Schaufelberger M

Published 2 December 2008 Volume 2009:5 Pages 13—19

DOI https://doi.org/10.2147/VHRM.S4129

Review by Single-blind

Peer reviewer comments 3


Mahsa Mohammadi1, Inger Ekman2, Maria Schaufelberger3

1Department of Medicine; 2Institute of Health and Care Sciences; 3Departments of Emergency and Cardiovascular Medicine, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden.

Objective: To investigate whether change in objective signs during up-titration of angiotensin-converting enzyme (ACE)-inhibitors in patients with chronic heart failure affect perception of information about medicines and subjective activities such as self-care.

Methods: Consecutive patients referred for up-titration of ACE-inhibitors were included. Patients were given the Satisfaction with Information about Medicines Scale and the European Heart Failure Self-Care Behaviour Scale at their first visit and when the target dose was reached. Blood pressure, pulse and s-creatinine were measured at each visit.

Results: Relationships were found between change in systolic (r = 0.224, p = 0.044) and diastolic (r = 0.361, p = 0.001) blood pressure and change in self-care scores and were also observed at baseline (r = 0.324, 0.398, p = 0.001, 0.000) and follow-up (r = 0.317, 0.253, p = 0.004, 0.022). Diastolic blood pressure correlated with the “potential problem of medication” score (r = −0.263, p = 0.007).

Conclusion: Patients with a more advanced disease usually have a lower blood pressure. Hence, the relationship between blood pressure and self-care scores might indicate that patients are more motivated to adhere to prescriptions the more advanced the stage of their disease.

Keywords: blood pressure, chronic heart failure, adherence, scales

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