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Refractive outcomes of an advanced aspherically optimized profile for myopia corrections by LASIK: a retrospective comparison with the standard aspherically optimized profile

Authors Meyer B, Sluyterman van Langeweyde G, Wottke M

Received 14 October 2014

Accepted for publication 18 November 2014

Published 23 February 2015 Volume 2015:9 Pages 379—392

DOI https://doi.org/10.2147/OPTH.S75812

Checked for plagiarism Yes

Review by Single-blind

Peer reviewer comments 3

Editor who approved publication: Dr Scott Fraser


Bertram Meyer,1 Georg Sluyterman van Langeweyde,2 Matthias Wottke2

1Augencentrum Köln, Cologne, Germany; 2Carl Zeiss Meditec AG, Jena, Germany

Purpose: A retrospective comparison of refractive outcomes of a new, aspherically optimized profile with an enhanced energy correction feature (Triple-A) and the conventionally used aspherically optimized profile (ASA, or aberration smart ablation) for correction of low-to-high myopia.
Setting: Augen-OP-Centrum, Cologne, Germany
Design: Retrospective nonrandomized comparative study
Methods: A central database at the Augen-OP-Centrum was used to gather retrospective data for low-to-high myopia (up to -10 D). One hundred and seven eyes (56 patients) were treated with the ASA profile, and 79 eyes (46 patients) were treated with the Triple-A profile. Postoperative outcomes were evaluated at 1 month, 3 months, 6 months, and 1 year follow-up time points.
Results: The Triple-A profile showed better predictability indicated by a significantly lower standard deviation of residuals (0.32–0.34 vs 0.36–0.44, Triple-A vs ASA) in the 6-month to 1-year period. The Triple-A group had better stability across all time intervals and achieved better postoperative astigmatism improvements with significantly lower scatter. This group achieved better safety at 1 year, with 100% of eyes showing no change or gain in Snellen lines, compared with 97% in the ASA group. A better safety index was observed for the Triple-A group at later time points. The Triple-A group had a better efficacy index and a higher percentage of eyes with an uncorrected Snellen visual acuity of 20/20 or greater at all investigated follow-up time points.
Conclusion: The new aspherically optimized Triple-A profile can safely and effectively correct low-to-high myopia. It has demonstrated superiority over the ASA profile in most refractive outcomes.

Keywords: Triple-A, wavefront measurements, corneal aberrations, corneal asphericity, ablation profile

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